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1

Discovery of Selective Irreversible Inhibitors for Bruton’s Tyrosine Kinase

Zhengying Pan, Heleen Scheerens, Shyr-Jiann Li, Brian E. Schultz, Paul A. Sprengeler, L. Chuck Burrill, Rohan V. Mendonca, Michael D. Sweeney, Keana C. K. Scott, Paul G. Grothaus, Douglas A. Jeffery,

Journal:

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

2

Molecular-dynamics simulations of slow copper cluster deposition

Rongwu, Lee, Zhengying, Pan, Yukun, Ho

Journal:

Physical Review B

Year:

1996

Language:

english

File:

PDF, 131 KB

english, 1996

3

ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma

Liu, Yalu, Wang, Xiaogan, Deng, Lijuan, Ping, Lingyan, Shi, Yunfei, Zheng, Wen, Lin, Ningjing, Wang, Xiaopei, Tu, Meifeng, Xie, Yan, Liu, Weiping, Ying, Zhitao, Zhang, Chen, Pan, Zhengying, Wang, Xi,

Journal:

Cancer Cell International

Year:

2019

Language:

english

File:

PDF, 8.51 MB

english, 2019

4

Multi-Feature Manifold Discriminant Analysis for Hyperspectral Image Classification

Huang, Hong, Li, Zhengying, Pan, Yinsong

Journal:

Year:

2019

Language:

english

File:

PDF, 47.26 MB

english, 2019

5

M3DNet: A manifold-based discriminant feature learning network for hyperspectral imagery

Li, Zhengying, Huang, Hong, Li, Yuan, Pan, Yinsong

Journal:

Expert Systems with Applications

Year:

2020

Language:

english

File:

PDF, 6.96 MB

english, 2020

6

Protein degradation through covalent inhibitor-based PROTACs

Xue, Gang, Chen, Jiahui, Liu, Lihong, Zhou, Danli, Zuo, Yingying, Fu, Tiancheng, Pan, Zhengying

Journal:

Chemical Communications

Year:

2020

Language:

english

File:

PDF, 2.27 MB

english, 2020

7

Polymer-Supported C2-Symmetric Ligands for Palladium-Catalyzed Asymmetric Allylic Alkylation Reactions

Barry M. Trost, Zhengying Pan, Jorge Zambrano, Christof Kujat

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

8

Polymer-Supported C2-Symmetric Ligands for Palladium-Catalyzed Asymmetric Allylic Alkylation Reactions

Barry M. Trost, Zhengying Pan, Jorge Zambrano, Christof Kujat

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 73 KB

english, 2002

9

Polymer-Supported C2-Symmetric Ligands for Palladium-Catalyzed Asymmetric Allylic Alkylation Reactions.

Barry M. Trost, Zhengying Pan, Jorge Zambrano, Christof Kujat

Journal:

Year:

2003

File:

PDF, 95 KB

2003

10

A Monte Carlo simulation of the effect of the surface oxide layer on blocking dips

Zhengying Pan, Peng Zhou

Journal:

Year:

1989

Language:

english

File:

PDF, 216 KB

english, 1989

11

Acceleration of gold atoms induced by aluminum clusters impacting on gold targets

Journal:

Physics Letters A

Year:

1993

Language:

english

File:

PDF, 277 KB

english, 1993

12

Development of activity-based probes for trypsin-family serine proteases

Zhengying Pan, Douglas A. Jeffery, Kareem Chehade, Jerlyn Beltman, James M. Clark, Paul Grothaus, Matthew Bogyo, Amos Baruch

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

13

Macrocyclic oligomers of isophthalic acid and trans-1,2-diaminocyclohexane — building blocks for synthetic peptide receptors

Zhengying Pan, W.Clark Still

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 208 KB

english, 1996

14

Investigation of low-energy carbon cluster depositions on surfaces by a molecular dynamics simulation

Zhengying Pan, Wenjun Zhu, Zhenyong Man, Yi Xu, Yukun Ho

Journal:

Surface and Coatings Technology

Year:

2000

Language:

english

File:

PDF, 287 KB

english, 2000

15

Interaction of slow (100 ev/atom) carbon clusters with gold: Penetration properties and collision cascades

Zhengying Pan, Peter Sigmund

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1990

Language:

english

File:

PDF, 872 KB

english, 1990

16

Molecular dynamics simulation of slow gold clusters impacting on gold

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1992

Language:

english

File:

PDF, 428 KB

english, 1992

17

Collision cascades induced by aluminum clusters impacting on gold thin films

Zhengying Pan, Jiayong Tang

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1994

Language:

english

File:

PDF, 347 KB

english, 1994

18

Molecular dynamics simulations of the C70–graphite interaction

Zhenyong Man, Zhengying Pan, Jun Xie, Yukun Ho

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1998

Language:

english

File:

PDF, 130 KB

english, 1998

19

Simulations of C60 in collision with diamond surfaces

Zhengying Pan, Jun Xie, Zhenyong Man

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1998

Language:

english

File:

PDF, 112 KB

english, 1998

20

Impact-induced chemisorption of C2H2 on diamond(0 0 1) surfaces: a molecular dynamics simulation

Wenjun Zhu, Zhengying Pan, Yukun Ho, Zhengyong Man

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1999

Language:

english

File:

PDF, 113 KB

english, 1999

21

Molecular dynamics study of C60–graphite interaction

Zhenyong Man, Zhengying Pan, Yukun Ho, Wenjun Zhu

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1999

Language:

english

File:

PDF, 109 KB

english, 1999

22

ChemInform Abstract: Reductant-Directed Formation of PS—PAMAM-Supported Gold Nanoparticles for Use as Highly Active and Recyclable Catalysts for the Aerobic Oxidation of Alcohols and the Homocoupling of Phenylboronic Acids.

Jie Zheng, Shengyue Lin, Xianhao Zhu, Biwang Jiang, Zhen Yang, Zhengying Pan

Journal:

Year:

2012

File:

PDF, 38 KB

2012

23

Reductant-directed formation of PS–PAMAM-supported gold nanoparticles for use as highly active and recyclable catalysts for the aerobic oxidation of alcohols and the homocoupling of phenylboronic acids

Zheng, Jie, Lin, Shengyue, Zhu, Xianhao, Jiang, Biwang, Yang, Zhen, Pan, Zhengying

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

24

Genetic association betweenp53codon 72 polymorphism and risk of cutaneous squamous cell carcinoma

Liu, Ting, Lei, Zeyuan, Pan, ZhengYing, Chen, Yu, Li, Xiang, Mao, TongChun, He, Qian, Fan, Dongli

Journal:

Year:

2014

Language:

english

File:

PDF, 214 KB

english, 2014

25

Discovery of a Series of 2,5-Diaminopyrimidine Covalent Irreversible Inhibitors of Bruton’s Tyrosine Kinase with in Vivo Antitumor Activity

Li, Xitao, Zuo, Yingying, Tang, Guanghui, Wang, Yan, Zhou, Yiqing, Wang, Xueying, Guo, Tianlin, Xia, Mengying, Ding, Ning, Pan, Zhengying

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

26

Benzo[ e ]isoindole-1,3-diones as Potential Inhibitors of Glycogen Synthase Kinase-3 (GSK-3). Synthesis, Kinase Inhibitory Activity, Zebrafish Phenotype, and Modeling of Binding Mode

Zou, Haixia, Zhou, Liyan, Li, Yuanzhen, Cui, Yi, Zhong, Hanbing, Pan, Zhengying, Yang, Zhen, Quan, Junmin

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 3.29 MB

english, 2010

27

Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I

Zhou, Yiqing, Guo, Tianlin, Li, Xitao, Dong, Yi, Galatsis, Paul, Johnson, Douglas S., Pan, Zhengying

Journal:

Year:

2014

Language:

english

File:

PDF, 454 KB

english, 2014

28

Synthesis of Highly Substituted Imidazolidine-2,4-dione (Hydantoin) through Tf 2 O-Mediated Dual Activation of Boc-Protected Dipeptidyl Compounds

Liu, Hui, Yang, Zhimin, Pan, Zhengying

Journal:

Organic Letters

Year:

2014

Language:

english

File:

PDF, 641 KB

english, 2014

29

Enhanced emissions of hard photons in heavy ion reactions by the particle correlation effect

Wang, Zhisong, Ho, Yukun, Pan, Zhengying

Journal:

Physical Review C

Year:

1994

Language:

english

File:

PDF, 280 KB

english, 1994

30

Site-Selective Protein Immobilization by Covalent Modification of GST Fusion Proteins

Zhou, Yiqing, Guo, Tianlin, Tang, Guanghui, Wu, Hui, Wong, Nai-Kei, Pan, Zhengying

Journal:

Bioconjugate Chemistry

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

31

A general approach for the development of fluorogenic probes suitable for no-wash imaging of kinases in live cells

Zhang, Qing, Liu, Hui, Pan, Zhengying

Journal:

Chemical Communications

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

32

HL-2M Divertor Geometry Exploration with SOLPS5.0

Cui, Xuewu, Pan, Yudong, Cui, Zhengying, Li, Jiaxian, Zhang, Jinhua, Mao, Rui

Journal:

Plasma Science and Technology

Year:

2013

Language:

english

File:

PDF, 285 KB

english, 2013

33

Impurity Measurement and Study on HL-2A Divertor Tokamak

Zhengying, Cui, Ping, Sun, Yudong, Pan, Wei, Li, Quanming, Wang, Xuru, Duan

Journal:

Plasma Science and Technology

Year:

2006

Language:

english

File:

PDF, 380 KB

english, 2006

34

Fission-like estimate for the emission of heavy clusters

Zhengying, Pan, Zhushu, Yuan, Fuchia, Yang

Journal:

Chinese Physics Letters

Year:

1986

Language:

english

File:

PDF, 227 KB

english, 1986

35

Impact-Parameter Dependence of the Electronic Energy Loss of Protons in Solids

Nengping, Wang, Yukun, Huo, Zhengying, Pan, Qiyun, Shao

Journal:

Chinese Physics Letters

Year:

1995

Language:

english

File:

PDF, 839 KB

english, 1995

36

Molecular Dynamics Simulation of Low-Energy C 60 in Collision with a Graphite (0001) Surface

Zhenyong, Man, Zhengying, Pan, Lei, Liu, Rongwu, Li

Journal:

Chinese Physics Letters

Year:

1995

Language:

english

File:

PDF, 291 KB

english, 1995

37

Computer Simulation of Surface Damages at Atomic Scale Induced by Cluster Impacting

Zhengying, Pan, Rongwu, Li, Yukun, Ho

Journal:

Chinese Physics Letters

Year:

1995

Language:

english

File:

PDF, 260 KB

english, 1995

38

ChemInform Abstract: Synthesis of Highly Substituted Imidazolidine-2,4-dione (Hydantoin) Through Tf 2 O-Mediated Dual Activation of Boc-Protected Dipeptidyl Compounds.

Liu, Hui, Yang, Zhimin, Pan, Zhengying

Journal:

Year:

2015

File:

PDF, 29 KB

2015

39

Inhibition of Anaphase-Promoting Complex by Silence APC/CCdh1to Enhance Radiosensitivity of Nasopharyngeal Carcinoma Cells

Wang, Chunmiao, Su, Zhengying, Hou, Huaxin, Li, Danrong, Pan, Zhiyu, Tian, Wei, Mo, Chunyan

Journal:

Journal of Cellular Biochemistry

Year:

2016

Language:

english

File:

PDF, 2.13 MB

english, 2016

40

A novel 2,5-diaminopyrimidine-based affinity probe for Bruton’s tyrosine kinase

Zuo, Yingying, Shi, Yanxia, Li, Xitao, Teng, Yingqi, Pan, Zhengying

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

41

Cell Cycle-dependent Degradation of the Methyltransferase SETD3 Attenuates Cell Proliferation and Liver Tumorigenesis

Cheng, Xiaoqing, Hao, Yuan, Shu, Wenjie, Zhao, Mengjie, Zhao, Chen, Wu, Yuan, Peng, Xiaodan, Yao, Pinfang, Xiao, Daibiao, Qing, Guoliang, Pan, Zhengying, Yin, Lei, Hu, Desheng, Du, Hai-Ning

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

42

The mTOR kinase inhibitor everolimus synergistically enhances the anti-tumor effect of the Bruton's tyrosine kinase (BTK) inhibitor PLS-123 on Mantle cell lymphoma

Li, Jiao, Wang, Xiaogan, Xie, Yan, Ying, Zhitao, Liu, Weiping, Ping, Lingyan, Zhang, Chen, Pan, Zhengying, Ding, Ning, Song, Yuqin, Zhu, Jun

Journal:

International Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

43

Effects of Rubiadin isolated from Prismatomeris connata on anti-hepatitis B virus activity in vitro

Peng, Zheng, Fang, Gang, Peng, Fenghui, Pan, Zhiyu, Su, Zhengying, Tian, Wei, Li, Danrong, Hou, Huaxin

Journal:

Phytotherapy Research

Year:

2017

Language:

english

File:

PDF, 618 KB

english, 2017

44

Covalent and selective immobilization of GST fusion proteins with fluorophosphonate-based probes

Wang, Xiafeng, Guo, Tianlin, Chen, Jiahui, Li, Xiaofeng, Zhou, Yiqing, Pan, Zhengying

Journal:

Chemical Communications

Year:

2018

Language:

english

File:

PDF, 2.39 MB

english, 2018

45

Development of a Selective Labeling Probe for Bruton’s Tyrosine Kinase Quantification in Live Cells

Chen, Jiahui, Wang, Xiafeng, He, Fengli, Pan, Zhengying

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 2.20 MB

english, 2018

46

Design and synthesis of (aza)indolyl maleimide-based covalent inhibitors of glycogen synthase kinase 3β

Yang, Zhimin, Liu, Hui, Pan, Botao, He, Fengli, Pan, Zhengying

Journal:

Organic & Biomolecular Chemistry

Year:

2018

Language:

english

File:

PDF, 1.36 MB

english, 2018

47

The Bruton’s tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages

Ping, Lingyan, Ding, Ning, Shi, Yunfei, Feng, Lixia, Li, Jiao, Liu, Yalu, Lin, Yufu, Shi, Cunzhen, Wang, Xing, Pan, Zhengying, Song, Yuqin, Zhu, Jun

Journal:

Year:

2017

Language:

english

File:

PDF, 3.19 MB

english, 2017

48

Discovery of an Orally Available Janus Kinase 3 Selective Covalent Inhibitor

Shi, Liyang, Zhong, Zhenpeng, Li, Xitao, Zhou, Yiqing, Pan, Zhengying

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 4.72 MB

english, 2019

49

Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma

Ding, Ning, Li, Xitao, Shi, Yunfei, Ping, Lingyan, Wu, Lina, Fu, Kai, Feng, Lixia, Zheng, Xiaohui, Song, Yuqin, Pan, Zhengying, Zhu, Jun

Journal:

Year:

2015

Language:

english

File:

PDF, 2.57 MB

english, 2015

50

Non-enzymatic glucose sensor based on ZnO–CeO2 whiskers

Qian, Junchao, Wang, Yaping, Pan, Jian, Chen, Zhigang, Wang, Chencheng, Chen, Jianping, Wu, Zhengying, Yangyue,

Journal:

Materials Chemistry and Physics

Year:

2020

Language:

english

File:

PDF, 8.09 MB

english, 2020